OR ChemPhosBio focuses on the chemistry of organophosphorus compounds as therapeutic agents for biomedical applications and as organocatalysts for the selective formation of C-C bonds.

the main areas of research are :

Methodological developments for the synthesis of organophosphorus compounds such as phosphonates, phosphinates, biphosphonates, bisphosphinates and phosphinylphosphonates.

The application of these methods to the synthesis of bioactive phosphorus derivatives and the evaluation of their biological activities (in vitro).

  The synthesis of peptide-like organic catalysts containing a phosphonic or phosphinic acid unit for the selective formation of C-C bonds.

Keywords: organophosphorus compounds, phosphonates, phosphinates, bisphosphonates, bisphosphinates, vectorisation, asymmetric organocatalysis